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Rationale, design and baseline characteristics of the Microbiome and Insulin Longitudinal Evaluation Study (MILES).
Measuring respiratory function in mice using unrestrained whole-body plethysmography.
An Innovative Seven-year Physician Scientist Residency Training Program That Addresses the Shortage of Academic Surgeons.
Should Public Health Literacy Be a Core Requirement for College Students?
Dietary fried fish intake increases risk of CVD: the REasons for Geographic And Racial Differences in Stroke (REGARDS) study.
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Hollis, Thomas
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Hollis, Thomas
Item Type
Name
Academic Article
Functional consequences of the RNase H2A subunit mutations that cause Aicardi-Goutieres syndrome.
Academic Article
The TREX1 exonuclease R114H mutation in Aicardi-Goutières syndrome and lupus reveals dimeric structure requirements for DNA degradation activity.
Academic Article
The TREX1 double-stranded DNA degradation activity is defective in dominant mutations associated with autoimmune disease.
Academic Article
Dominant mutation of the TREX1 exonuclease gene in lupus and Aicardi-Goutieres syndrome.
Academic Article
Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase.
Academic Article
Defects in DNA degradation revealed in crystal structures of TREX1 exonuclease mutations linked to autoimmune disease.
Concept
Autoimmune Diseases
Concept
Autoimmune Diseases of the Nervous System
Academic Article
The TREX1 C-terminal region controls cellular localization through ubiquitination.
Academic Article
The Arg-62 residues of the TREX1 exonuclease act across the dimer interface contributing to catalysis in the opposing protomers.
Academic Article
SAMHD1: Recurring roles in cell cycle, viral restriction, cancer, and innate immunity.
Grant
Structure and Regulation of the TREX1 Exonuclease
Search Criteria
Autoimmune Diseases